Helmut Habazettl

• DFG 1999-2002: Microcirculation of the Isolated Heart (Principal Investigator)
• DFG 2000-2003: Leikocyte Thrombocyte Interactions in Myocardial Reperfusion Injury (Co-Investigator
• Berlin Bed Rest Study 2007/08 Microvascular Adapatations to Microgravity (Principal Investigator)
• DLR 2012/13 National Centrifuge Program: Microvascular Adapatations to (Hyper-) Gravity
• ESA 2015/16 Longterm Bed Rest Study: Microvascular Adapatations to Microgravity (Principal Investigator)

1: Louvaris Z, Vogiatzis I, Aliverti A, Habazettl H, Wagner H, Wagner P, Zakynthinos S. Blood flow does not redistribute from respiratory to leg muscles during exercise breathing heliox or oxygen in COPD. J Appl Physiol (1985). 2014 Aug 1;117(3):267-76. doi:  0.1152/japplphysiol.00490.2014. Epub 2014 Jun 5.

2: Redlin M, Habazettl H, Schoenfeld H, Kukucka M, Boettcher W, Kuppe H, Salama A. Red blood cell storage duration is associated with various clinical outcomes in pediatric cardiac surgery. Transfus Med Hemother. 2014 Apr;41(2):146-51. doi: 10.1159/000357998. Epub 2014 Feb 17. PubMed PMID: 24847191;

3: Kukucka M, Pasic M, Habazettl H, Unbehaun A, Dreysse S, Drews T, Hillebrandt T, Mladenow A, Buz S. Contrast echocardiography: a novel technique for assessment of total aortic regurgitation following transapical aortic valve implantation. Eur J Cardiothorac Surg. 2014 Feb 28. [Epub ahead of print]

4: Redlin M, Boettcher W, Kukucka M, Kuppe H, Habazettl H. Blood transfusion during versus after cardiopulmonary bypass is associated with postoperative morbidity in neonates undergoing cardiac surgery. Perfusion. 2014 Jan 6;29(4):327-332.

5: Enigk F, Wagner A, Samapati R, Rittner H, Brack A, Mousa SA, Schäfer M, Habazettl H, Schäper J. Thoracic epidural anesthesia decreases endotoxin-induced endothelial injury. BMC Anesthesiol. 2014 Apr 5;14:23.

6: Treskatsch S, Feldheiser A, Rosin AT, Sifringer M, Habazettl H, Mousa SA, Shakibaei M, Schäfer M, Spies CD. A modified approach to induce predictable congestive heart failure by volume overload in rats. PLoS One. 2014 Jan 31;9(1):e87531.

7: Redlin M, Kukucka M, Boettcher W, Schoenfeld H, Huebler M, Kuppe H, Habazettl H. Blood transfusion determines postoperative morbidity in pediatric cardiac surgery applying a comprehensive blood-sparing approach. J Thorac Cardiovasc Surg. 2013 Sep;146(3):537-42.

8: Vogiatzis I, Louvaris Z, Habazettl H, Andrianopoulos V, Wagner H, Roussos C, Wagner PD, Zakynthinos S. Cerebral cortex oxygen delivery and exercise limitation in patients with COPD. Eur Respir J. 2013 Feb;41(2):295-301.

9: Kukucka M, Pasic M, Dreysse S, Mladenow A, Habazettl H, Hetzer R, Unbehaun A. Patient-prosthesis mismatch after transapical aortic valve implantation: incidence and impact on survival. J Thorac Cardiovasc Surg. 2013 Feb;145(2):391-7.

10: Schäper J, Wagner A, Enigk F, Brell B, Mousa SA, Habazettl H, Schäfer M. Regional sympathetic blockade attenuates activation of intestinal macrophages and reduces gut barrier failure. Anesthesiology. 2013 Jan;118(1):134-42.

11: Louvaris Z, Zakynthinos S, Aliverti A, Habazettl H, Vasilopoulou M, Andrianopoulos V, Wagner H, Wagner P, Vogiatzis I. Heliox increases quadriceps muscle oxygen delivery during exercise in COPD patients with and without dynamic hyperinflation. J Appl Physiol (1985). 2012 Oct;113(7):1012-23.

12: Kukucka M, Stepanenko A, Potapov E, Krabatsch T, Kuppe H, Habazettl H. Impact of tricuspid valve annulus dilation on mid-term survival after implantation of a left ventricular assist device. J Heart Lung Transplant. 2012 Sep;31(9):967-71.

13: Kukucka M, Pasic M, Unbehaun A, Dreysse S, Mladenow A, Habazettl H, Hetzer R. Hemodynamic characteristics of Edwards Sapien aortic valve prosthesis assessed with transesophageal echocardiography. J Heart Valve Dis. 2012 Sep;21(5):662-9.

14: Neye N, Enigk F, Shiva S, Habazettl H, Plesnila N, Kuppe H, Gladwin MT, Kuebler WM. Inhalation of NO during myocardial ischemia reduces infarct size and improves cardiac function. Intensive Care Med. 2012 Aug;38(8):1381-91.

15: Redlin M, Habazettl H, Boettcher W, Kukucka M, Schoenfeld H, Hetzer R, Huebler M. Effects of a comprehensive blood-sparing approach using body weight-adjusted miniaturized cardiopulmonary bypass circuits on transfusion requirements in pediatric cardiac surgery. J Thorac Cardiovasc Surg. 2012 Aug;144(2):493-9.

16: Kukucka M, Pasic M, Dreysse S, Buz S, Drews T, Mladenow A, Habazettl H, Kuppe H, Unbehaun A, Hetzer R. Patient-prosthesis mismatch after transapical aortic valve implantation. Ann Cardiothorac Surg. 2012 Jul;1(2):172-5.

17: Redlin M, Huebler M, Boettcher W, Kukucka M, Schoenfeld H, Hetzer R, Habazettl H. Minimizing intraoperative hemodilution by use of a very low priming volume cardiopulmonary bypass in neonates with transposition of the great arteries. J Thorac Cardiovasc Surg. 2011 Oct;142(4):875-81.

18: Vogiatzis I, Louvaris Z, Habazettl H, Athanasopoulos D, Andrianopoulos V, Cherouveim E, Wagner H, Roussos C, Wagner PD, Zakynthinos S. Frontal cerebral cortex blood flow, oxygen delivery and oxygenation during normoxic and hypoxic exercise in athletes. J Physiol. 2011 Aug 15;589(Pt 16):4027-39.

19: Vogiatzis I, Habazettl H, Aliverti A, Athanasopoulos D, Louvaris Z, LoMauro A, Wagner H, Roussos C, Wagner PD, Zakynthinos S. Effect of helium breathing on intercostal and quadriceps muscle blood flow during exercise in COPD patients. Am J Physiol Regul Integr Comp Physiol. 2011 Jun;300(6):R1549-59.

20: Redlin M, Huebler M, Boettcher W, Kuppe H, Hetzer R, Habazettl H. How near-infrared spectroscopy differentiates between lower body ischemia due to arterial occlusion versus venous outflow obstruction. Ann Thorac Surg. 2011 Apr;91(4):1274-6.

21: O’Brien B, Pasic M, Kuppe H, Hetzer R, Habazettl H, Kukucka M. A transapical or transluminal approach to aortic valve implantation does not attenuate the inflammatory response. Heart Surg Forum. 2011 Apr;14(2):E110-3.

22: Mousa SA, Shaqura M, Schäper J, Treskatsch S, Habazettl H, Schäfer M, Abdul-Khaliq H. Developmental expression of δ-opioid receptors during maturation of the parasympathetic, sympathetic, and sensory innervations of the neonatal heart: early targets for opioid regulation of autonomic control. J Comp Neurol. 2011 Apr 1;519(5):957-71.

23: Kukucka M, Potapov E, Stepanenko A, Weller K, Mladenow A, Kuppe H, Habazettl H. Acute impact of left ventricular unloading by left ventricular assist device on the right ventricle geometry and function: effect of nitric oxide inhalation. J Thorac Cardiovasc Surg. 2011 Apr;141(4):1009-14.

24: Kukucka M, Stepanenko A, Potapov E, Krabatsch T, Redlin M, Mladenow A, Kuppe H, Hetzer R, Habazettl H. Right-to-left ventricular end-diastolic diameter ratio and prediction of right ventricular failure with continuous-flow left ventricular assist devices. J Heart Lung Transplant. 2011 Jan;30(1):64-9.

25: Huebler M, Habazettl H, Boettcher W, Kuppe H, Hetzer R, Redlin M. Transfusion-free complex cardiac surgery: with use of deep hypothermic circulatory arrest in a preterm 2.96-kg Jehovah’s witness neonate. Tex Heart Inst J. 2011;38(5):562-4.

26: Vogiatzis I, Athanasopoulos D, Habazettl H, Aliverti A, Louvaris Z, Cherouveim E, Wagner H, Roussos C, Wagner PD, Zakynthinos S. Intercostal muscle blood flow limitation during exercise in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2010 Nov 1;182(9):1105-13.

27: Mousa SA, Shaqura M, Schäper J, Huang W, Treskatsch S, Habazettl H, Abdul-Khaliq H, Schäfer M. Identification of mu- and kappa-opioid receptors as potential targets to regulate parasympathetic, sympathetic, and sensory neurons within rat intracardiac ganglia. J Comp Neurol. 2010 Sep 15;518(18):3836-47.

28: Belavý DL, Bock O, Börst H, Armbrecht G, Gast U, Degner C, Beller G, Soll H, Salanova M, Habazettl H, Heer M, de Haan A, Stegeman DF, Cerretelli P, Blottner D, Rittweger J, Gelfi C, Kornak U, Felsenberg D. The 2nd Berlin BedRest Study: protocol and implementation. J Musculoskelet Neuronal Interact. 2010 Sep;10(3):207-19.

29: Schäper J, Ahmed R, Perschel FH, Schäfer M, Habazettl H, Welte M. Thoracic epidural anesthesia attenuates endotoxin-induced impairment of gastrointestinal organ perfusion. Anesthesiology. 2010 Jul;113(1):126-33.

30: Habazettl H, Athanasopoulos D, Kuebler WM, Wagner H, Roussos C, Wagner PD, Ungruhe J, Zakynthinos S, Vogiatzis I. Near-infrared spectroscopy and indocyanine green derived blood flow index for noninvasive measurement of muscle perfusion during exercise. J Appl Physiol (1985). 2010 Apr;108(4):962-7.