Charité in Space - The Center for Space Medicine Berlin (ZWMB)

SAM_6694 

PROF. DR.  DIETER BLOTTNER

Center for Space Medicine Berlin
Charité Cross Over Charitéplatz 1 
10117 Berlin

Email Me

+49 (0)30 450 528 347

Dieter Blottner studied biology, human medicine, and English and American literature at the University of Mainz, Regensburg and Marburg. He wrote his thesis (PhD) on the embryonic development of teeth. After his Postdoc positions in Anatomy and Cell Biology Department at Marburg University, he wrote his habilitation thesis at the Freie University of Berlin on neuronal growth factors of the autonomic nervous system in 1992. Since 1993, his main research focus is on skeletal muscle signaling and plasticity and adaptation of the neuromuscular system.   Research Focus

  •  autonomic nervous system
  •  skeletal muscle structure, plasticity and adaptation
  •  neuromuscular system in health and disuse
  •  exercise countermeasures (bed rest, spaceflight)
  •  Space Life Sciences

Studies and Grants

  • DLR 2001-2003: Skeletal muscle atrophy in male bed rest (PI, LTBR-Study Toulouse, France)
  • DLR 2003-2005: Skeletal muscle signaling (PI, 1st Berlin-BedRest Study, BBR-1, Charité)
  • DLR 2005-2007: Muscle atrophy in female bed rest (PI, WISE Study, Toulouse, France)
  • DLR 2007-2009: Nitric Oxide Signaling in Disuse and Exercise (PI, 2nd Berlin BedRest Study)
  • DLR 2010-2013: Nutritional Intervention in Bed Rest (PI, MEP Study, DLR, Cologne)
  • DLR 2014-2017: Mice on International Space Station (CoPi, MDS mission) and on biosatellite (PI, BION M1), CoPI, Nitrosative stress in disuse (2015 ESA Bed Rest Study, Toulouse, France)

Recent References
1. Salanova M, Gelfi C, Moriggi M, Vasso M, Viganò A, Minafra L, Bonifacio G, Schiffl G, Gutsmann M, Felsenberg D, Cerretelli P, Blottner D. Disuse deterioration of human skeletal muscle challenged by resistive exercise superimposed with vibration: evidence from structural and proteomic analysis. FASEB J. 2014 Aug 13. pii: fj.14-252825. [Epub ahead of print]

2. Luxa N, Salanova M, Schiffl G, Gutsmann M, Besnard S, Denise P, Clarke A, Blottner D. Increased myofiber remodelling and NFATc1-myonuclear translocation in rat postural skeletal muscle after experimental vestibular deafferentation. J Vestib Res. 2013;23(4-5):187-93. doi: 10.3233/VES-130499.

3. Salanova M, Schiffl G, Gutsmann M, Felsenberg D, Furlan S, Volpe P, Clarke A, Blottner D.Nitrosative stress in human skeletal muscle attenuated by exercise countermeasure after chronic disuse. Redox Biol. 2013 Oct 28;1(1):514-26. doi: 10.1016/j.redox.2013.10.006. eCollection 2013.

4. Salanova M, Volpe P, Blottner D.Homer protein family regulation in skeletal muscle and neuromuscular adaptation. IUBMB Life. 2013 Sep;65(9):769-76. doi: 10.1002/iub.1198. Epub 2013 Aug 5. Review.

5. Sun LW, Blottner D, Luan HQ, Salanova M, Wang C, Niu HJ, Felsenberg D, Fan YB. Bone and muscle structure and quality preserved by active versus passive muscle exercise on a new stepper device in 21 days tail-suspended rats. J Musculoskelet Neuronal Interact. 2013 Jun;13(2):166-77.

6. Mueller-Wohlfahrt HW, Haensel L, Mithoefer K, Ekstrand J, English B, McNally S, Orchard J, van Dijk CN, Kerkhoffs GM, Schamasch P, Blottner D, Swaerd L, Goedhart E, Ueblacker P. Terminology and classification of muscle injuries in sport: the Munich consensus statement. Br J Sports Med. 2013 Apr;47(6):342-50. doi: 10.1136/bjsports-2012-091448. Epub 2012 Oct 18.

7. Sandonà D, Desaphy JF, Camerino GM, Bianchini E, Ciciliot S, Danieli-Betto D, Dobrowolny G, Furlan S, Germinario E, Goto K, Gutsmann M, Kawano F, Nakai N, Ohira T, Ohno Y, Picard A, Salanova M, Schiffl G, Blottner D, Musarò A, Ohira Y, Betto R, Conte D, Schiaffino S. Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission. PLoS One. 2012;7(3):e33232. doi: 10.1371/journal.pone.0033232. Epub 2012 Mar 28.